User:Mr. Ibrahem/Alcoholic ketoacidosis

Mr. Ibrahem/Alcoholic ketoacidosis
Other namesAlcoholic ketosis, alcoholic acidosis[1]
It generally occurs in chronic alcoholics or those who binge drink[2]
SpecialtyInternal medicine
SymptomsAbdominal pain, vomiting, agitation, fast respiratory rate, specific "fruity" smell[2]
Risk factorsAlcoholism, binge drinking[2]
Diagnostic methodBased on symptoms[2]
Differential diagnosisOther causes of high anion gap metabolic acidosis (diabetic ketoacidosis, toxic alcohol ingestion, starvation ketosis), pancreatitis[2][3]
TreatmentIntravenous fluids, thiamine[2]
PrognosisGood with treatment[1]

Alcoholic ketoacidosis (AKA) is a specific group of symptoms and metabolic state related to alcohol use.[3] Symptoms often include abdominal pain, vomiting, agitation, a fast respiratory rate, and a specific "fruity" smell.[2] Consciousness is generally normal.[1] Complications may include sudden death.[1]

AKA most commonly occurs in long term alcoholics and less commonly in those who binge drink.[2] Onset is generally after a decreased ability to eat for a few days.[2] Diagnosis is generally based on symptoms.[2] Blood sugar levels are often normally or only mildly increased.[2] Other conditions that may present similarly include other causes of high anion gap metabolic acidosis including diabetic ketoacidosis.[2]

Treatment is generally with intravenous normal saline and intravenous sugar solution.[2] Thiamine and measures to prevent alcohol withdrawal are also recommended.[2] Treatment of low blood potassium may also be required.[2] Those who are affected are most frequently between the ages of 20 and 60.[2] The condition was initially recognized in 1940 and named in 1971.[3]

References edit

  1. ^ a b c d McGuire, LC; Cruickshank, AM; Munro, PT (June 2006). "Alcoholic ketoacidosis". Emergency Medicine Journal. 23 (6): 417–20. doi:10.1136/emj.2004.017590. PMC 2564331. PMID 16714496.
  2. ^ a b c d e f g h i j k l m n o p Howard, RD; Bokhari, SRA (January 2019). Alcoholic Ketoacidosis (AKA). PMID 28613672.
  3. ^ a b c Allison, MG; McCurdy, MT (May 2014). "Alcoholic metabolic emergencies". Emergency Medicine Clinics of North America. 32 (2): 293–301. doi:10.1016/j.emc.2013.12.002. PMID 24766933.