Eugenia Kumacheva
Eugenia Kumacheva at the Royal Society admissions day in London in 2016
Born
Odessa, Soviet Union
NationalityRussian-Canadian
Alma materTechnical University (B.S.), Technical University (M.Sc.), , Russian Academy of Science.(Ph.D)
AwardsL’Oreal –UNECO Women in Science Prize (2008-2009), Fellow to the Royal Society of Canada (2007), Fellow of the Royal Society (2016)
Scientific career
FieldsChemistry
InstitutionsUniversity of Toronto
Websitewww.chem.utoronto.ca/staff/EK/

Eugenia Kumacheva[1]

edit

Eugenia Kumacheva is a chemistry faculty at the University of Toronto and a Canada Research Chair in Advanced Functional Materials her research interests span across the fields of fundamental and applied polymers science , nanotechnology, microfluidics, and interface chemistry[2]. In 2011, she published a book titled "Microfluidic Reactors for Polymer Particles "[3] co-authored with Piotr Garstecki. She is currently a tier 1 Canadian researcher in Advanced Polymer Materials and also a Fellow of Royal Society of Canada [3]

Biography and Career

edit

Eugenia Kumacheva was born in OdessaSoviet Union. After earning her undergraduate degree (cum laude) from Technical University in St. Petersburg[4], Kumacheva worked in industry for several years before moving to Moscow where she obtained her  Ph.D. degree at the Russian Academy of Sciences in 1981[4]. Her research focused on the physical chemistry of polymers. Kumacheva then worked as a research assistant at the Moscow State University [5]before beginning her post-doctorate fellowship supported by Minerva Foundation with Professor Jacob Klein at the Weizmann Institute of Science in Israel[5]. She then joined the research lab of Mitchel Winnick at the University of Toronto in Canada to study multicomponent polymer systems. In 1996, Kumacheva was hired as an Assistant Professor at the University of Toronto Chemistry Department, and in 2005, she was promoted to a Full Professor[5]. During her career, Kumacheva has delivered numerous public lectures, co-authored a book, and has been recognized by a number of national and international awards. In 2008, she was the first Canadian recipient of the L'Oréal-UNESCO "Women in Science" Prize.[6] Her book titled “Microfluid reactor for Polymer Particles[4]” was published in 2011, and describes about the use of liquid flow through microscopic channels as a method of polymerization.[3]

Research

edit
 
Copolymerization of a hetero polymer composed of gold and palladium will form tightly linked nanochains when mixing together in polar solvent[7] Credit: Angew. Chem. Int. Ed

Kumacheva’s work focuses on polymer sciencenanosciencemicrofluidics, and interface chemistry. She has a strong effort in biomimetic research focused biological tissuesfluids, and environments with polymers and nanomaterials. Kumacheva has been involved with important developments in modeling the biological conditions of myocardial infarctions, strokes, pulmonary embolism, and various other blood related disorders or health conditions using polymers and nano-materials. Some of this work is related to mimicking blood vessels in order to gain a greater understanding of the chemistry and physics involved in blood clots. Kumacheva has been involved in research exploring the potential of microbubbles, a gas enclosed by a natural or synthetic polymer for both diagnostic and therapeutic applications such as targeted drug delivery and molecular imaging. An additional medical application of Kumacheva’s work is the creation of hydrogels [8]and various other chemical environments to either support the life of a stem cell, affect necrotic heart tissue as well as deter the metastasis of cancer cells. Kumacheva has been involved in research involving cellulose nanocrystals (CNCs) and fluorescenlatex nanoparticles (NPs[9]), as well as self-assembling nanocubes. 

Quantifying the efficiency of CO2 capture by Lewis Pairs [10]

edit
 
The mechanism by which the Lewis pair binds CO2 in solution. The amount of conjugated Lewis pairs can be measured and reflects the quantity of CO2 in solution.
 
Inside oscillatory microfluidic tube, the Switchable Hydrophilicity Solvent (SHS) - in this case DBAE - being protonated and becoming hydrophilic. The hydrophilic state contains bound CO2.

Much of her work relates to climate change and lowering CO2 levels. She has collaborated with Doug Stephan (University of Toronto), to investigate the behavior of frustrated Lewis pairs used to separate various elements of natural gas; namely, ethylene from a mixture of ethylene and methane. This work has great industrial importance due to the need for efficient and precise separation of petroleum compounds in various industries.

Study of Extraction and Recycling of Switchable Hydrophilicity Solvents in an Oscillatory Microfluidic Platform[11]

edit

In another study involving frustrated Lewis pairs, Kumacheva used them to quantify the efficiency of binding CO2 emissions. Measuring the amount of CO2 bound by the Lewis pairs provided information on the amount that was captured into solution. Some of the reactions in CO2 uptake require solvents with different properties, but it is expensive to prepare multiple solvents. As a solution to this problem, Kumacheva has worked on solvents with adjustable properties such as hydrophilicity called switchable hydrophilicity solvents (SHS). For example, a sterically hindered, large, hydrophobic molecule (Dibutylethanol Amine – DBAE) being protonated to become hydrophilic as necessitated by the reaction process.

Year Award
1992 Minerva Foundation Fellowship (Germany)
1994 Imperial College Visiting Fellowship (UK)
1999 Premier Research Excellence Award (Canada)
2000 International Chorafas Foundation Award
2002 Recipient of Canada Research Chair in Advanced Polymer Materials/Tier 2
2003 Schlumberger Scholarship (Oxford University, UK)
2004 Clara Benson Award (CIC Award)
2005 Macromolecular Science and Engineer Award, CIC
2006 Recipient of Canada Research Chair in Advanced Polymer Materials/ Tier 1
2007 Elected as Fellow to the Royal Society of Canada (Canadian National Academy of Science).

The 2007 E. Gordon Young Lecturer of The Chemical Institute of Canada

2008-2009 L'Oréal-UNESCO Women in Science Prize (Laureate for North America[6])
2009 Japan-Canada WISET lectureship, Royal Society of Canada
2010 Killam Research Fellowship, Canada Council for the Arts
2011 Distinguished Lecturer, The University of Western Ontario, Canada.

Connaught Innovation Award, Connaught Foundation.

2012 Humboldt Research Award, Alexander von Humboldt Foundation (Germany).

Inventor of the Year, University of Toronto

2013 University Professor (distinction given to <2% of Faculty at the University of Toronto)
2016 Elected as Fellow of the Royal Society (FRS) (British National Academy of Science)
2017 Canada Institute of Chemistry (CIC) Medal

References

edit
  1. ^ "Eugenia Kumacheva". royalsociety.org. Retrieved 2017-06-05.
  2. ^ Wong, Patrick. "Research". www.chem.utoronto.ca. Retrieved 2017-06-05.
  3. ^ a b Kumacheva, Eugenia; Garstecki, Piotr (2011). Microfluidic Reactors for Polymer Particles - Kumacheva - Wiley Online Library. doi:10.1002/9780470979228. ISBN 9780470057735.
  4. ^ a b "Professor Eugenia Kumacheva". University of Toronto.
  5. ^ a b c "Staff: Eugenia Kumacheva". University of Toronto.
  6. ^ a b "2009 Edition Of The L'Oréal-Unesco For Women In Science Awards - L'Oréal Group". www.loreal.com. Retrieved 2017-05-12.
  7. ^ Liu, Kun; Lukach, Ariella; Sugikawa, Kouta; Chung, Siyon; Vickery, Jemma; Therien-Aubin, Heloise; Yang, Bai; Rubinstein, Michael; Kumacheva, Eugenia (2014-03-03). "Copolymerization of Metal Nanoparticles: A Route to Colloidal Plasmonic Copolymers". Angewandte Chemie International Edition. 53 (10): 2648–2653. doi:10.1002/anie.201309718. ISSN 1521-3773. PMC 4000723. PMID 24520012.
  8. ^ Wang, Yihe; Li, Yunfeng; Thérien-Aubin, Héloïse; Ma, Jennifer; Zandstra, Peter W.; Kumacheva, Eugenia (2016-01-01). "Two-dimensional arrays of cell-laden polymer hydrogel modules". Biomicrofluidics. 10 (1): 014110. doi:10.1063/1.4940430. PMC 4723409. PMID 26858822.
  9. ^ Querejeta-Fernández, Ana; Kopera, Bernd; Prado, Karen S.; Klinkova, Anna; Methot, Myriam; Chauve, Grégory; Bouchard, Jean; Helmy, Amr S.; Kumacheva, Eugenia (2015-10-27). "Circular Dichroism of Chiral Nematic Films of Cellulose Nanocrystals Loaded with Plasmonic Nanoparticles". ACS Nano. 9 (10): 10377–10385. doi:10.1021/acsnano.5b04552. ISSN 1936-0851. PMID 26336902.
  10. ^ Chi, Jay J.; Johnstone, Timothy C.; Voicu, Dan; Mehlmann, Paul; Dielmann, Fabian; Kumacheva, Eugenia; Stephan, Douglas W. (2017-03-28). "Quantifying the efficiency of CO2 capture by Lewis pairs". Chemical Science. 8 (4): 3270–3275. doi:10.1039/C6SC05607E. ISSN 2041-6539. PMC 5424443. PMID 28553530.
  11. ^ Lestari, Gabriella; Alizadehgiashi, Moien; Abolhasani, Milad; Kumacheva, Eugenia (2017-05-01). "Study of Extraction and Recycling of Switchable Hydrophilicity Solvents in an Oscillatory Microfluidic Platform". ACS Sustainable Chemistry & Engineering. 5 (5): 4304–4310. doi:10.1021/acssuschemeng.7b00339.