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Overview

Ganirelix, also marketed as Antagon, and the active ingredient in Orgalutran, is a drug that is sometimes used to regulate pituitary hormone secretions in women undergoing fertility treatment ^[1]. It allows the regular timing of the surges of hormones involved in the Hypothalamic-Pituitary-Gonadal axis to be controlled exogenously. Ganirelix is a competitive gonadotropin releasing hormone ^[1].

apple ^[2]

GnRH agaonists

Location of the hypothalamus. GnRH is released from the hypothalamus, and subsequently acts on GnRH receptors on the anterior pituitary.

References

^ ^a ^b Oberyé, J (2000 Feb). "Local tolerance, pharmacokinetics, and dynamics of ganirelix (Orgalutran) administration by Medi-Jector compared to conventional needle injections". Human Reproduction (Oxford, England). 15 (2): 245–9. doi:10.1093/humrep/15.2.245. PMID 10655292. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)
^ Organon Pharmaceuticals USA. "Ganirelix Acetate Injection". Archived Drug Label. Retrieved 11 May 2012.

Category:Fertility medicine

[one-1] Oberyé, J (2000 Feb). "Local tolerance, pharmacokinetics, and dynamics of ganirelix (Orgalutran) administration by Medi-Jector compared to conventional needle injections". Human Reproduction (Oxford, England). 15 (2): 245–9. doi:10.1093/humrep/15.2.245. PMID 10655292. {{cite journal}}: Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

[Label-2] Organon Pharmaceuticals USA. "Ganirelix Acetate Injection". Archived Drug Label. Retrieved 11 May 2012.

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