Tweety family member 2

Tweety family member 2 is a protein that in humans is encoded by the TTYH2 gene.[5] Members of this family function as chloride channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene.

TTYH2
Identifiers
AliasesTTYH2, C17orf29, Tweety family member 2
External IDsOMIM: 608855 MGI: 2157091 HomoloGene: 41882 GeneCards: TTYH2
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for TTYH2
Genomic location for TTYH2
Band17q25.1Start74,213,571 bp[1]
End74,262,020 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032646
NM_052869
NM_001330453

NM_053273

RefSeq (protein)

NP_001317382
NP_116035
NP_443101

NP_444503

Location (UCSC)Chr 17: 74.21 – 74.26 MbChr 11: 114.68 – 114.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141540 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034714 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tweety family member 2".

Further readingEdit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.