Thiosulfate—thiol sulfurtransferase
(Redirected from Thiosulfate-thiol sulfurtransferase)
In enzymology, a thiosulfate-thiol sulfurtransferase (EC 2.8.1.3) is an enzyme that catalyzes the chemical reaction
| thiosulfate-thiol sulfurtransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.1.3 | ||||||||
| CAS no. | 111070-24-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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- thiosulfate + 2 glutathione sulfite + glutathione disulfide + sulfide
Thus, the two substrates of this enzyme are thiosulfate and glutathione, whereas its 3 products are sulfite, glutathione disulfide, and sulfide.
This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:thiol sulfurtransferase. Other names in common use include glutathione-dependent thiosulfate reductase, sulfane reductase, and sulfane sulfurtransferase. This enzyme participates in glutathione metabolism.
References
edit- PECK HD, FISHER E (1962). "The oxidation of thiosulfate and phosphorylation in extracts of Thiobacillus thioparus". J. Biol. Chem. 237: 190–7. doi:10.1016/S0021-9258(18)81384-9. PMID 14484816.
- Sido B; Koj A (1972). "Separation of rhodanese and thiosulfate reductase activities in carp liver extracts". Acta Biol. Cracow Ser. Zool. 15: 97–103.
- Uhteg LC, Westley J (1979). "Purification and steady-state kinetic analysis of yeast thiosulfate reductase". Arch. Biochem. Biophys. 195 (1): 211–22. doi:10.1016/0003-9861(79)90343-6. PMID 383018.
