Tetraprenyl-beta-curcumene synthase

Tetraprenyl-β-curcumene synthase (EC 4.2.3.130, ytpB (gene)) is an enzyme with systematic name all-trans-heptaprenyl-diphosphate diphosphate-lyase (cyclizing, tetraprenyl-β-curcumene-forming).[1] This enzyme catalyses the following chemical reaction

Tetraprenyl-β-curcumene synthase
Identifiers
EC no.4.2.3.130
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
all-trans-heptaprenyl diphosphate tetraprenyl-β-curcumene + diphosphate

This enzyme is isolated from Bacillus subtilis.

References

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  1. ^ Sato T, Yoshida S, Hoshino H, Tanno M, Nakajima M, Hoshino T (June 2011). "Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase". Journal of the American Chemical Society. 133 (25): 9734–7. doi:10.1021/ja203779h. PMID 21627333.
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