Template:Did you know nominations/Li–Fraumeni syndrome

The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: rejected by reviewer, closed by Launchballer talk 13:45, 20 July 2024 (UTC)

Li–Fraumeni syndrome

  • ... that Li–Fraumeni syndrome is characterized by early onset of cancer, a wide variety of types of cancers, often rare, and development of multiple primary cancers throughout one's life?
  • Hisada M, Garber JE, Fung CY, Fraumeni JF Jr, Li FP. Multiple primary cancers in families with Li-Fraumeni syndrome. J Natl Cancer Inst. 1998 Apr 15;90(8):606-11. doi: 10.1093/jnci/90.8.606. PMID: 9554443.
  • Reviewed:
  • Comment: With the increased access to genetic testing, more people are being diagnosed with a variant in their TP53 gene (a tumor suppressor). TP53 is the most studied human genome in the world. When it doesn't work correctly, multiple cancers can develop in individuals. It has decimated families with early cancer deaths but genetic testing followed by appropriate imaging and screening can result in early cancer detection - and that can save lives. Li-Fraumeni syndrome can also affect cancer treatment.[1]
5x expanded by Germlinep53 (talk). Number of QPQs required: 0. Nominator has less than 5 past nominations.

Germlinep53 (talk) 16:26, 19 July 2024 (UTC).

Policy compliance:

Hook eligibility:

  • Cited: No - Very generic source, not verifiable.
  • Interesting: Unknown
  • Other problems: No - Hook doesn't make sense grammatically—not even sure what it's saying.
QPQ: None required.
Overall: According to the DYK check tool, Assuming article is at 5x now, expansion began 293 edits ago on February 12, 2012. Please see WP:DYKNEW for the newness requirement for DYK, which this article doesn't appear to meet in any way. Sorry to bear the bad news, but I need to reject this nomination because it fails quite a few of our criteria. Please review our guidelines for the future. Happy editing! Bsoyka (tcg) 16:42, 19 July 2024 (UTC)
  1. ^ Hisada M, Garber JE, Fung CY, Fraumeni JF Jr, Li FP. Multiple primary cancers in families with Li-Fraumeni syndrome. J Natl Cancer Inst. 1998 Apr 15;90(8):606-11. doi: 10.1093/jnci/90.8.606. PMID: 9554443.