Tandem charges are effective against reactive armour, which is designed to protect an armoured vehicle (mostly tanks) against anti-tank munitions. The first stage of the weapon is typically a weak charge that either pierces the reactive armour of the target without detonating it leaving a channel through the reactive armour so that the second warhead may pass unimpeded, or simply detonating the armourplate causing the timing of the counter-explosion to fail. The second detonation from the same projectile (which defines it as a tandem charge) attacks the same location as the first detonation where the reactive armour has been compromised. Since the regular armour plating is often the only defence remaining, the main charge (second detonation) has an increased likelihood of penetrating the armour.
However, tandem-charges are useful only against ERA (explosive reactive armour) types of reactive armour, much less so against the non-explosive reactive armour (NxRA) types, since their inner liner is not explosive itself and thus not expended by the small forward warhead of tandem-charge attack.
The PG-7VR warhead for the RPG-7 rocket launcher and the PG-29V warhead for the more modern RPG-29 rocket launcher are examples of tandem charges, but the technology is employed worldwide because they were designed in the Cold War era to counter the reactive armour that was a common feature on Soviet tanks. Examples of missiles that use tandem charges include the BGM-71 TOW, FGM-148 Javelin, Brimstone and the MBT LAW.
Dual charges are also effective at increasing the effectiveness of warheads when used against structures (such as bunkers). Because the explosion of a unitary high explosive charge will follow the path of least resistance, much of the explosive power of a warhead will be lost to the air surrounding the target if detonated outside the structure. This effect can be countered by using heavily constructed gravity bombs with delay fuzes which penetrate the earth, concrete, etc. of the target before exploding—thus containing the explosion inside the structure and significantly increasing its effect.
Gravity bombs require aircraft to fly rather close to what may be a heavily-defended target which poses a significant risk to the launch aircraft. Cruise missiles equipped with large tandem-charge warheads can use the first charge to create a hole into which the missile flies before exploding the second charge, creating a similar effect of the delayed gravity bomb. An example of an anti-structure tandem-charge warhead is the BROACH warhead.