Talk:Time release technology
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Talk Page edit
Welcome to the talk page of Sustained Release.--Delma1 12:06, 21 December 2006 (UTC)
In medical terms : explain delayed release. eg.,Ecosprin tablet what does it do
Explain Extended release. eg., Metolor XR capsule what does it do in the body?
- I'm not sure where to put this, but there are two more articles with similar content. Being so short I think it makes sense to combine them. I am not too familiar with the subject so I won't do it myself, but I thought it makes sense to tell. Added links:
http://en.wikipedia.org/wiki/Slow-release http://en.wikipedia.org/wiki/Sustained_release_dosage_forms — Preceding unsigned comment added by Celerity2 (talk • contribs) 23:31, 15 May 2012 (UTC)
Time control question edit
How finely can the release be controlled? Say, if I wanted a drug to be released only after eight hours, what would be the variance in the actual release time? Thanks. --Amit 12:46, 7 March 2007 (UTC)
That would be controlled release - sustained just means over extended periods of time. Release can be e.g. controlled from capsules. Either the complete capsule or a small part of it dissolve after a certain time and the drug is released completly or partially. —Preceding unsigned comment added by 70.45.146.25 (talk) 00:18, 6 August 2008 (UTC)
Terrible to start of with a confusion. edit
Sustained release is not the same as controlled release. Controlled means that the drug level is controlled - it can be pulsating etc. Sustained means that the drug is delievered for prolonged times (which can mean hours to months). I found a definition which I felt was more accurate than the statement in the article that states that the release rate has zero order kinetics (I challenge that statement!). Controlled release: Delivery of an agent at a controlled rate for an extended time. A controlled rate is not necessarily constant which is zero order.
Controlled release covers other factors than time. For example pH - for Enteric Coatings, that protect protein molecules in the low pH of the stomach, then release them in the higher pH of the duodenum. Or vaginal pessaries or deposits, which control release to specific phases of the menstrual cycle.
Second, the article basically covers only conventional methods and drugs - not included is, e.g., micro- and nanosphere formulation with biocompatible polymers which is important for the delivery of many biodrugs (e.g., proteins).
When I have the time I include something here. I own many images of release formulations, such as micro- and nanospheres.
Dr. Kai Griebenow —Preceding unsigned comment added by 70.45.146.25 (talk) 00:24, 6 August 2008 (UTC)
Sustained release is not the same as controlled release. The page was started as discussing sustained release but was then expanded to include other forms Time Release medicines. I have moved the page to appropriate location. --Obsolete.fax (talk) 03:11, 3 November 2008 (UTC)
question need help edit
anyone can help to answer the difference between the sustained relaease versus the extended released? thanks very much for the help —Preceding unsigned comment added by 204.114.196.11 (talk) 13:35, 9 October 2008 (UTC)
Acute Tolerance edit
Should a section be created for the possibility of acute tolerance leading to reduced efficacy because of extended release Rhowensd (talk) 01:44, 3 May 2016 (UTC)Rhowensd