Talk:Tesofensine

Latest comment: 14 years ago by Zaphraud in topic Cocaine

Added some data to the drug box. Data taken from the following article, and references therein: Bilz0r (talk) 09:05, 23 October 2008 (UTC)Reply

Lehr T, Staab A, Tillmann C; et al. (2007). "Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease". British journal of clinical pharmacology. 64 (1): 36–48. doi:10.1111/j.1365-2125.2007.02855.x. PMC 2000606. PMID 17324246. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link) 

Check the PubChem structure linked to this article. Absolutely incorrect.--ChemSpiderMan (talk) 16:55, 20 December 2007 (UTC)Reply

Removed. -- Ed (Edgar181) 16:14, 21 December 2007 (UTC)Reply

Cocaine edit

Tesofensine and cocaine have very similar structures and inhibit reuptake of the same three neurotransmitters. We should sniff out some sourced commentary about this... Wnt (talk) 18:19, 13 January 2009 (UTC)Reply

Yeah, no kidding. It looks exactly like someone familiar with the differences between zoloft and tametraline decided to make a more serotonergic version of troparil, then decided while they were wiping out vulnerable ester linkages they'd go ahead and make the other one into the ether version of cocaethylene. 100% recycled subgroups from other drugs here. Zaphraud (talk) 00:47, 12 May 2009 (UTC)Reply