Talk:Discovery and development of renin inhibitors

References needing formatting

• Brown
• Cumin
• Szelke2
• Gradman
• Novartis
• FDA

--ἀνυπόδητος (talk) 19:52, 28 September 2011 (UTC)

Assessment

This is a good and rather in-depth overview of the topic, and well sourced. I think it could be structured a bit more systematically, which would make it easier to read – for example, the mechanism of the RAAS and renin is spread out across several sections. I added two tags: one for the image of H-142 which isn't explained (I suppose it's a first-generation renin inhibitor but it needs to say), and one for the last sentence which is borderline promotional with only the manufacturer's website as a source. Calling it "next generation" is a now well-established way to make drugs look better than they are (like levocetirizine which is only the eutomer of the second-generation antihistamine cetirizine but has been labelled "third-generation" by its inventor).

Overall, I'll give this article a C class assessment. Please feel free to ask if you have questions about this. --ἀνυπόδητος (talk) 18:08, 1 October 2011 (UTC)