Talk:Cushing's syndrome/Archive 1

Messy!

This is messy. When I have the time I will tidy it up, but I can't say when! Jfdwolff 12:11, 8 Mar 2004 (UTC)

Please tell this in a normal way!

As with most medical articles, this explanation of a seemingly important disease is very mysterious in its explanation. It is explained in a "doctors" way, and not understandable to the general public. It should be better explained in a way that most people who have not gone to medical school can understand. —Preceding unsigned comment added by 70.124.132.176 (talk • contribs) 02:44, 9 April 2006

I have tried to give a new perspective to this page that will hopefully allow it to be better understood. Tell me what you think and if there are some areas that still don't make a lot of sense--William mcfadden 16:38, 18 February 2007 (UTC)

This article requires a total rewrite as it is completely unintelligible to 90% of its readers, it is impossible to read as any flow is destroyed by the constant use of technical rather than common language. This article is completely useless as it stands for the purposes of Wikipedia. —Preceding unsigned comment added by 92.11.10.119 (talk) 06:06, 21 December 2008 (UTC)

Thank you for your suggestion. When you feel an article needs improvement, please feel free to make those changes. Wikipedia is a wiki, so anyone can edit almost any article by simply following the edit this page link at the top. The Wikipedia community encourages you to be bold in updating pages. Don't worry too much about making honest mistakes — they're likely to be found and corrected quickly. If you're not sure how editing works, check out how to edit a page, or use the sandbox to try out your editing skills. New contributors are always welcome. You don't even need to log in (although there are many reasons why you might want to). WhatamIdoing (talk) 05:41, 22 December 2008 (UTC)

Species?

From the article it seems to be an entirely human disease. I understand dogs can get it as well. Any other species? Copey 2 16:11, 29 September 2006 (UTC)

I second the question. It seems to be entirely aimed at humans, but dogs can certainly get it too. It'd be interesting to read more about it from a canine pathology perspective. 82.1.87.184 (talk) 20:46, 4 November 2013 (UTC)

Title of Article

As I understand it, the title should be Cushing Syndrome, not Cushing's Syndrome, because Cushing did not have it, but only discovered. I have also been told that this is a new phenomena. Should we change it?

I would only object to the change due to the fact that it is normally referred to as Cushing's Syndrome clinically. I am not suggesting that this is politically correct terminology, but it is the most common name that the disease is given.--William mcfadden 23:30, 16 February 2007 (UTC)

Image

I feel that rather than the molecular structure of cortisol, perhaps a different image might be more appropriate. Does anyone know of any histological images that would suffice, perhaps available in the public/government domain? --JE.at.UWO^U|_T 14:14, 14 November 2006 (UTC)

Merge Cushing's disease to Cushing's syndrome

I agree that the disease and the syndrome ought to have separate entries - they are different things, however similar and related. If they had names that were more different (which other hormonal diseases with similar relationships do) we would not even be asking. —Preceding unsigned comment added by 24.147.81.239 (talk) 22:57, 1 February 2011 (UTC)

Cushing Disease ought to have a separate entry from Cushing's Syndrome —The preceding unsigned comment was added by 134.84.246.50 (talk) 00:36, 29 January 2007 (UTC).

I entirely agree with this statement. Cushing was a doctor that studied the brain and the disease cushing disease is characterized by a tumor of the pituitary gland. Cushing syndrome is entirely different. It is a tumor in the adrenal gland. Cushings syndrome can also be characterized by anything that causes an excess in cortisol secretion. It makes a big difference where the tumor is in the body even though the net effect of both diseases is excess cortisol in the blood.--William mcfadden 23:29, 1 February 2007 (UTC)

At first it would seem that splitting up Cushings disease and Cushings syndrome would be a good idea. However, the outcomes of both diseases are exactly the same, elevated cortisol. Both conditions are manifest exactly the same, so I thought that it would be better to just define Cushings disease in the article. It didn't give a clear definition in the title or in the pathology section, so I modified both sections. People also said that this article was confusing, so I have added a little background that might assist in understanding the pathology associated with this disease.--William mcfadden 22:57, 16 February 2007 (UTC)

02/21/2008: The entry needs to be separated and rewritten. Cushing’s Syndrome is a result of steroid use. Cushing’s Disease is a result of a tumor on the pituitary. The article is misleading. If one has doubts, they should consider going to John Hopkins website and reviewing the article on Cushing’s disease. http://www.hopkinsneuro.org/pituitary/disease.cfm/condition/Cushings_Disease --Behavior_Surgeon —Preceding comment was added at 06:45, 22 February 2008 (UTC)

Cushing's syndrome and Cushing's disease are different. A syndrome is a collection of symptoms. It may not point to a particular diagnosis (disease). Cushing's syndrome has many different causes, and Cushing's disease is only one of them. Cushing's syndrome and Cushing's disease may have similar symptoms (I must stress that Cushing syndrome due to different causes do have slightly different presentation - particularly about hirsutism), but the two conditions have totally different causes, biochemistry (it's not just elevated cortisol - there are different patterns of elevation of different corticosteroids and mineralocorticoids) and, thus, treatment.218.103.142.199 (talk) 16:05, 26 November 2008 (UTC)

26/02/2010 Maybe you should add to the treatment section that in some cases of Cushing Disease radiotherapy is used. Although the page on radiotherapy is a bit rubbish. I can't find any sources for you but have personal experience. Thanks —Preceding unsigned comment added by 82.41.214.86 (talk) 20:54, 26 February 2010 (UTC)

I'd say keep them separate, as per Behavior Surgeon. Also, although it can be explained in a combined article what separates the terms, a mere redirection of Cushing's disease into Cushing syndrome can be enough for some people to get the incorrect idea that they are synonymous. Mikael Häggström (talk) 10:34, 1 April 2011 (UTC)

cushings in dogs

what are normal cortisol levels what is high —Preceding unsigned comment added by 207.7.160.167 (talk) 23:32, 6 July 2008 (UTC)

VetMed?

Do we want to roll the veterinary medicine aspects into this article (see recent addition), or move that into a separate, dedicated article? WhatamIdoing (talk) 04:30, 9 January 2009 (UTC)

I think the veterinary stuff should be moved to a different page or be lumped in a separate section. I find it ridiculous that there is a list of symptoms in dogs but not in humans. Horus (talk) 22:44, 9 February 2009 (UTC)

The article does contain information about the symptoms in humans. I've marked it so that it's easier to find. WhatamIdoing (talk) 20:14, 10 February 2009 (UTC)

Vandalism

This edit was basically vandalism. I've restored the obvious things, like the infobox and the categories, but do we want the veterinary stuff here, or in another article? It shouldn't just get "lost". WhatamIdoing (talk) 06:22, 9 March 2009 (UTC)

Plethora of what?

I moved the following line from symptoms: a plethora over the cheeks, anterior neck, and V of the chest,. The only meaning of plethora I found was that in Wiktionary of An excess of red blood cells or bodily humours, and I think it needs some specification before reinsertion. Mikael Häggström (talk) 18:02, 11 February 2010 (UTC)

Source #6

I wanted to look at source #6, but apparently you have to pay $15 to view the article. Besides the obvious absurdity, are these types of sources allowed? I'm not very familiar with wikipedia rules and guidelines (I will read them after this), but I wouldn't think sources that are not readily available to everyone should be included. —Preceding unsigned comment added by Darktangent (talk • contribs) 04:26, 31 March 2010 (UTC)

'A Wikipedia article should cite the best and most reliable sources regardless of whether they require a fee or a subscription.' Answered my own question. From the Wikipedia page on sources for medical topics. —Preceding unsigned comment added by Darktangent (talk • contribs) 04:32, 31 March 2010 (UTC)

Autoimmune?

The article states that Cushing's was the first autoimmune disease found in humans, yet that is the only instance of any mention of autoimmune. Autoimmune isn't listed as one of the causes, nor is Cushing's listed on the autoimmune page as one of those diseases. So, if Cushing's is or can be caused by autoimmune, there should be more information regarding that aspect of the disease. —Preceding unsigned comment added by Darktangent (talk • contribs) 03:08, 1 April 2010 (UTC)

Assessment comment

The comment(s) below were originally left at Talk:Cushing's syndrome/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

The description about the dexamethosone test isn't accurate. I'm not enough of an expert to fix it, but i can tell the gist of what is in the article is wrong.

Last edited at 03:53, 25 April 2007 (UTC). Substituted at 14:36, 1 May 2016 (UTC)