Talk:Butanilicaine

Latest comment: 7 years ago by Enigma55 in topic References

References

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Following are a few sources I've found about butanilicaine.

Because of the lack of information online, I assume Sanofi-Aventis (now Sanofi) has stopped making it. The drug was marketed as Hostacain, under two forms: butanilicaine hydrochloride or butanilicaine phosphate (if someone could check this out, I would appreciate).

The drug has been used on humans, horses, and frogs. Butanilicaine phosphate was administered by injection, as a 0.5 to 3% solution. It was used in the making of stable solutions of hydrogenated ergotalkaloids (US patent US 4402949).

  • Literature References: Prepn: Häussler, Ther, Arzneim.-Forsch. 3, 609 (1953); GB 726080 (1955 to Polymer Corp.); GB 759744 (1956 to Cilag); GB 782971; G. Ehrhart et al., US 2912460 (1957, 1959 both to Hoechst); Epstein, Kaminsky, J. Am. Chem. Soc. 80, 1892 (1958). Structure activity study: P. P. Koelzer, K. H. Wehr, Arzneim.-Forsch. 8, 181 (1958).
  • Effects on peripheral nerve function

H. Gerhard Vogel, by Wolfgang H. Vogel — Preceding unsigned comment added by Enigma55 (talkcontribs) 20:19, 5 January 2017 (UTC)Reply