Tetraspanin-31 is a protein that in humans is encoded by the TSPAN31 gene.[5]

TSPAN31
Identifiers
AliasesTSPAN31, SAS, tetraspanin 31
External IDsOMIM: 181035; MGI: 1914375; HomoloGene: 4359; GeneCards: TSPAN31; OMA:TSPAN31 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005981
NM_001330168
NM_001330169

NM_025982

RefSeq (protein)

NP_001317097
NP_001317098
NP_005972

NP_080258

Location (UCSC)Chr 12: 57.74 – 57.75 MbChr 10: 126.9 – 126.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135452Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000006736Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: TSPAN31 tetraspanin 31".

Further reading

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