TRAK1

Trafficking kinesin-binding protein 1 is a protein that in humans is encoded by the TRAK1 gene.

TRAK1
Identifiers
Aliases	TRAK1, MILT1, OIP106, trafficking kinesin protein 1, EIEE68, DEE68
External IDs	OMIM: 608112; MGI: 1914345; HomoloGene: 25103; GeneCards: TRAK1; OMA:TRAK1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3p22.1 Start 42,013,802 bp End 42,225,890 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9 F4|9 72.41 cM Start 121,126,568 bp End 121,303,984 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte paraflocculus of cerebellum muscle of thigh epithelium of bronchus pylorus bronchial epithelial cell right auricle epithelium of nasopharynx nipple frontal pole Top expressed in aortic valve ascending aorta muscle of thigh myocardium of ventricle superior frontal gyrus zygote ankle joint dentate gyrus of hippocampal formation granule cell stria vascularis lip More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding GABA receptor binding TPR domain binding signaling receptor binding myosin binding Cellular component cytoplasm endosome early endosome mitochondrion nucleus axon cytoplasm dendrite axonal growth cone perinuclear region of cytoplasm cytoplasmic vesicle dendrite cytoplasm cell cortex membrane mitochondrial membranes Biological process regulation of transcription by RNA polymerase II protein targeting protein O-linked glycosylation endosome to lysosome transport anterograde axonal transport of mitochondrion axonal transport of mitochondrion dendrite morphogenesis positive regulation of axonogenesis anterograde axonal transport protein localization neurogenesis vesicle transport along microtubule mitochondrion distribution Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22906 67095 Ensembl ENSG00000182606 ENSMUSG00000032536 UniProt Q9UPV9 Q6PD31 RefSeq (mRNA) NM_001042646 NM_001265608 NM_001265609 NM_001265610 NM_014965 NM_001349245 NM_001349246 NM_001349247 NM_001349248 NM_001349249 NM_175114 NM_001357968 NM_001357969 NM_001357970 NM_001357972 NM_001357973 RefSeq (protein) NP_001036111 NP_001252537 NP_001252538 NP_001252539 NP_055780 NP_001336174 NP_001336175 NP_001336176 NP_001336177 NP_001336178 NP_780323 NP_001344897 NP_001344898 NP_001344899 NP_001344901 NP_001344902 Location (UCSC) Chr 3: 42.01 – 42.23 Mb Chr 9: 121.13 – 121.3 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Iyer SP, Hart GW (2003). "Roles of the tetratricopeptide repeat domain in O-GlcNAc transferase targeting and protein substrate specificity". J. Biol. Chem. 278 (27): 24608–16. doi:10.1074/jbc.M300036200. PMID 12724313.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Brickley K, Smith MJ, Beck M, Stephenson FA (2005). "GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin". J. Biol. Chem. 280 (15): 14723–32. doi:10.1074/jbc.M409095200. PMID 15644324.
• Ozyildirim AM, Wistow GJ, Gao J, et al. (2005). "The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts". Invest. Ophthalmol. Vis. Sci. 46 (5): 1572–80. CiteSeerX 10.1.1.123.3574. doi:10.1167/iovs.04-1380. PMID 15851553.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Fransson S, Ruusala A, Aspenström P (2006). "The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking". Biochem. Biophys. Res. Commun. 344 (2): 500–10. doi:10.1016/j.bbrc.2006.03.163. PMID 16630562.