Transmembrane protein 219 also known as insulin-like growth factor-binding protein 3 receptor or IGFBP-3R is a protein that in humans is encoded by the TMEM219 gene.[5] IGFBP-3R acts as a cell death receptor for IGFBP3.[6]

TMEM219
Identifiers
AliasesTMEM219, IGFBP-3R, transmembrane protein 219
External IDsMGI: 1915992; HomoloGene: 19263; GeneCards: TMEM219; OMA:TMEM219 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083613
NM_194280

NM_026827
NM_028389
NM_001374613

RefSeq (protein)

NP_001077082
NP_919256
NP_001356617
NP_001356618
NP_001356619

NP_081103
NP_082665
NP_001361542

Location (UCSC)Chr 16: 29.94 – 29.97 MbChr 7: 126.49 – 126.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000149932Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060538Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Transmembrane protein 219".
  6. ^ Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y (September 2010). "Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer". J. Biol. Chem. 285 (39): 30233–46. doi:10.1074/jbc.M110.122226. PMC 2943278. PMID 20353938.