THAP4

THAP domain-containing protein 4 is a protein that in humans is encoded by the THAP4 gene.

THAP4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3IA8
Identifiers
Aliases	THAP4, PP238, CGI-36, THAP domain containing 4, Nb(III)
External IDs	OMIM: 612533; MGI: 1914276; HomoloGene: 12075; GeneCards: THAP4; OMA:THAP4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q37.3 Start 241,584,405 bp End 241,637,158 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 D Start 93,629,657 bp End 93,682,586 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart mucosa of transverse colon right auricle muscle of thigh left ventricle gastrocnemius muscle human kidney renal medulla putamen caudate nucleus Top expressed in seminiferous tubule spermatocyte choroid plexus of fourth ventricle epithelium of stomach spermatid right kidney tail of embryo human kidney large intestine left colon More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding DNA binding nucleic acid binding heme binding protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cellular component Biological process biological process regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51078 67026 Ensembl ENSG00000176946 ENSMUSG00000026279 UniProt Q8WY91 Q6P3Z3 RefSeq (mRNA) NM_001164356 NM_015963 NM_025920 NM_001310761 RefSeq (protein) NP_001157828 NP_057047 NP_001297690 NP_080196 Location (UCSC) Chr 2: 241.58 – 241.64 Mb Chr 1: 93.63 – 93.68 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.