Synaptojanin 1 is a protein that in humans is encoded by the SYNJ1 gene. [5]

SYNJ1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYNJ1, INPP5G, PARK20, synaptojanin 1, EIEE53, DEE53
External IDsOMIM: 604297; MGI: 1354961; HomoloGene: 48252; GeneCards: SYNJ1; OMA:SYNJ1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_203446
NM_001160302
NM_001160306
NM_003895

NM_001045515
NM_001164483

RefSeq (protein)

NP_001153774
NP_001153778
NP_003886
NP_982271

n/a

Location (UCSC)Chr 21: 32.63 – 32.73 MbChr 16: 90.73 – 90.81 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159082Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022973Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Synaptojanin 1". Retrieved 2016-03-13.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.