Swine vesicular disease

Swine vesicular disease (SVD) is an acute, contagious viral disease of swine caused by swine vesicular disease virus, an Enterovirus.[1] It is characterized by fever and vesicles with subsequent ulcers in the mouth and on the snout, feet, and teats. The pathogen is relatively resistant to heat,[citation needed] and can persist for a long time in salted, dried, and smoked meat products.[2] Swine vesicular disease does not cause economically important disease, but is important due to its similarity to foot-and-mouth disease.[3]

Swine vesicular disease virus
Virus classification e
(unranked): Virus
Realm: Riboviria
Phylum: incertae sedis
Order: Picornavirales
Family: Picornaviridae
Genus: Enterovirus
Species: Enterovirus B
Swine vesicular disease virus


Swine vesicular disease is most commonly brought into a herd by the introduction of a subclinically infected pig.[2] The disease can be transmitted in feed containing infected meat scraps,[4] or by direct contact with infected feces (such as in an improperly cleaned truck).

Clinical signsEdit

After an incubation period up to 7 days, the signs associated with swine vesicular disease occur.[5] The first sign is a transient mild fever.[5] Other signs include:

  • Vesicles in the mouth and on the snout and feet
  • Lameness and an unsteady gait, shivering, and jerking–type leg movements
  • Ruptured vesicles can cause ulcers on limbs and feet, and foot pads may be loosened.

Young animals are more severely affected. Recovery often occurs within a week. Mortality is negligible.

Swine vesicular disease has the same clinical signs as foot-and-mouth disease, and can only be diagnosed by laboratory testing.[4]

Prevention and controlEdit

No vaccine exists for SVD. Prevention measures are similar to those for foot-and-mouth disease: controlling animals imported from infected areas, sanitary disposal of garbage from international aircraft and ships, and thorough cooking of garbage. Infected animals should be placed in strict quarantine. Eradication measures for the disease include quarantining infected areas, depopulation and disposal of infected and contact pigs, and cleaning and disinfecting contaminated premises.


Swine vesicular disease was first identified in Italy in 1966.[6] In 1971, an outbreak occurred in Hong Kong,[6] and the disease was subsequently found other countries in Europe and Asia.[4]


  1. ^ "Genus: Enterovirus" (html). International Committee on Taxonomy of Viruses. Retrieved 21 August 2019. Swine vesicular disease virus is a variant of coxsackievirus B5 and causes a vesicular disease in pigs clinically indistinguishable from foot-and-mouth disease (genus Aphthovirus) and vesicular disease in pigs caused by Seneca Valley virus (genus Senecavirus).
  2. ^ a b "Technical disease card: Swine vesicular disease" (PDF). World Organisation for Animal Health. 2013. Retrieved 2017-07-16.
  3. ^ Maclachlan, NJ; Dubovi, EJ, eds. (2010). "Swine vesicular disease virus". Fenner's Veterinary Virology (5th ed.). Academic Press. pp. 489–90. ISBN 9780128011706.
  4. ^ a b c Murphy, FA; Gibbs, PJ; Horzinek, MC; Studdert, SJ (1999). "Swine vesicular disease". Veterinary virology (3rd ed.). San Diego: Academic Press. p. 523. ISBN 9780080552033.
  5. ^ a b Quinn, PJ; Markey, BK; Leonard, FC; Hartigan, P; Fanning, S; Fitzpatrick, ES (2011). Veterinary Microbiology and Microbial Disease (2nd ed.). Hoboken: John Wiley & Sons. p. 685. ISBN 9781118251164.
  6. ^ a b Mahy, Brian W.J. (2009). "Swine vesicular disease virus (SVDV)". The dictionary of virology (4th ed.). Amsterdam: Elsevier/Academic Press. p. 459. ISBN 9780080920368.