Sulfopropanediol 3-dehydrogenase

Sulfopropanediol 3-dehydrogenase (EC 1.1.1.308, DHPS 3-dehydrogenase (sulfolactate forming), 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming), dihydroxypropanesulfonate 3-dehydrogenase, hpsN (gene)) is an enzyme with systematic name (R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase.[1] This enzyme catalyses the following chemical reaction

Sulfopropanediol 3-dehydrogenase
Identifiers
EC no.1.1.1.308
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O (R)-3-sulfolactate + 2 NADH + 2 H+

The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.

References

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  1. ^ Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM (May 2010). "2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase". Microbiology. 156 (Pt 5): 1556–64. doi:10.1099/mic.0.037580-0. PMID 20150239.
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