Sulfoacetaldehyde dehydrogenase

Sulfoacetaldehyde dehydrogenase (EC 1.2.1.73, SafD) is an enzyme with systematic name 2-sulfoacetaldehyde:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

Sulfoacetaldehyde dehydrogenase
Identifiers
EC no.1.2.1.73
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
2-sulfoacetaldehyde + H2O + NAD+ sulfoacetate + NADH + 2 H+

This reaction is part of a bacterial pathway that can make use the amino group of taurine as a sole source of nitrogen for growth.

References

edit
  1. ^ Krejcík Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH (August 2008). "Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase". Archives of Microbiology. 190 (2): 159–68. doi:10.1007/s00203-008-0386-2. PMID 18506422.
edit