Sterol 3beta-glucosyltransferase

In enzymology, a sterol 3beta-glucosyltransferase (EC 2.4.1.173) is an enzyme that catalyzes the chemical reaction

sterol 3-beta-glucosyltransferase
Identifiers
EC no.2.4.1.173
CAS no.123940-38-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
UDP-glucose + a sterol UDP + a sterol 3-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and sterol, whereas its two products are UDP and sterol 3-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:sterol 3-O-beta-D-glucosyltransferase. Other names in common use include UDPG:sterol glucosyltransferase, UDP-glucose-sterol beta-glucosyltransferase, sterol:UDPG glucosyltransferase, UDPG-SGTase, uridine diphosphoglucose-poriferasterol glucosyltransferase, uridine diphosphoglucose-sterol glucosyltransferase, sterol glucosyltransferase, sterol-beta-D-glucosyltransferase, and UDP-glucose-sterol glucosyltransferase.

References

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  • Duperon R; Duperon P (1987). "Intracellular-localization of UDP-glucose-sterol glucosyl transferase and UDP-galactose-sterol galactosyl transferase activities in the leaves of tomato (Solanum lycopersicon L, Solanaceae)". Comptes Rendus de l'Académie des Sciences, Série III. 304: 235–238.
  • Kalinowska M; Wojciechowski ZA (1986). "Enzymatic-synthesis of nuatigenin 3-beta-D-glucoside in oat (Avena sativa) leaves". Phytochemistry. 25 (11): 2525–2529. doi:10.1016/S0031-9422(00)84501-X.
  • Kalinowska M; Wojciechowski ZA (1987). "Subcellular-localization of UDPG-nuatigenin glucosyltransferase in oat leaves". Phytochemistry. 26 (2): 353–357. doi:10.1016/S0031-9422(00)81413-2.
  • Murakami-Murofushi K, Ohta J (1989). "Expression of UDP-glucose: poriferasterol glucosyltransferase in the process of differentiation of a true slime mold, Physarum polycephalum". Biochim. Biophys. Acta. 992 (3): 412–5. doi:10.1016/0304-4165(89)90108-6. PMID 2528379.
  • Wojciechowski ZA, Zimowski J, Tyski S (1977). "Enzymatic synthesis of steryl 3beta-D-monoglucosides in the slime mold Physarum polycephalum". Phytochemistry. 16 (7): 911–914. doi:10.1016/S0031-9422(00)86691-1.