Spheroidene monooxygenase

Spheroidene monooxygenase (EC 1.14.15.9, CrtA, acyclic carotenoid 2-ketolase, spirilloxantin monooxygenase, 2-oxo-spirilloxanthin monooxygenase) is an enzyme with systematic name spheroidene, reduced-ferredoxin:oxygen oxidoreductase (spheroiden-2-one-forming).[1][2] This enzyme catalyses the following chemical reaction

Spheroidene monooxygenase
Identifiers
EC no.1.14.15.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
spheroidene + reduced ferredoxin + O2 spheroiden-2-one + oxidized ferredoxin + H2O
spirilloxantin + reduced ferredoxin + O2 2-oxospirilloxanthin + oxidized ferredoxin + H2O
2'-oxospirilloxanthin + reduced ferredoxin + O2 2,2'-dioxospirilloxanthin + oxidized ferredoxin + H2O

The enzyme is involved in spheroidenone biosynthesis and in 2,2'-dioxospirilloxanthin biosynthesis.

References

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  1. ^ Lee PC, Holtzapple E, Schmidt-Dannert C (November 2010). "Novel activity of Rhodobacter sphaeroides spheroidene monooxygenase CrtA expressed in Escherichia coli". Applied and Environmental Microbiology. 76 (21): 7328–31. doi:10.1128/AEM.01606-10. PMC 2976243. PMID 20851979.
  2. ^ Gerjets T, Steiger S, Sandmann G (February 2009). "Catalytic properties of the expressed acyclic carotenoid 2-ketolases from Rhodobacter capsulatus and Rubrivivax gelatinosus". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1791 (2): 125–31. doi:10.1016/j.bbalip.2008.12.006. PMID 19136077.
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