Scytalidopepsin A (EC 3.4.23.31, Scytalidium aspartic proteinase A, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum aspartic proteinase A-2, Scytalidium lignicolum aspartic proteinase A-I, Scytalidium lignicolum aspartic proteinase C, Scytalidium lignicolum carboxyl proteinase, Scytalidium lignicolum acid proteinase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
| Scytalidopepsin A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.23.31 | ||||||||
| CAS no. | 42613-34-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO3H)7-Gly and Leu17-Val in the B chain of insulin
This enzyme is isolated from the fungus Scytalidium lignicolum.
References
edit- ^ Oda K, Murao S (1974). "Purification and some enzymatic properties of acid protease A and B of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 38: 2435–2444. doi:10.1271/bbb1961.38.2435.
- ^ Oda K, Murao S (1976). "Action of Scytalidium lignicolum acid proteases on insulin B-chain". Agric. Biol. Chem. 40: 1221–1225. doi:10.1271/bbb1961.40.1221.
- ^ Oda K, Torishima H, Murao S (1986). "Purification and characterization of acid proteinase C of Scytalidium lignicolum ATCC 24568". Agric. Biol. Chem. 50: 651–658. doi:10.1271/bbb1961.50.651.
External links
edit- Scytalidopepsin+A at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
