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Santa Isabel (Spanish pronunciation: [ˈsanta isaˈβel]) is a town and municipality in the Tolima department of Colombia. The population of the municipality was 6,220 as of the 1993 census.

Santa Isabel, Tolima
Municipality and town
Flag of Santa Isabel, Tolima
Flag
Official seal of Santa Isabel, Tolima
Seal
Location of the municipality and town of Santa Isabel, Tolima in the Tolima Department of Colombia.
Location of the municipality and town of Santa Isabel, Tolima in the Tolima Department of Colombia.
Country Colombia
DepartmentTolima Department
Area
 • Total416 km2 (161 sq mi)
Elevation
2,250 m (7,380 ft)
Population
 (2016)
 • Total6,382
Time zoneUTC-5 (Colombia Standard Time)

Coordinates: 4°43′00″N 75°06′05″W / 4.71667°N 75.1014°W / 4.71667; -75.1014