Surfeit locus protein 6 is a protein that in humans is encoded by the SURF6 gene.[5][6]

SURF6
Identifiers
AliasesSURF6, RRP14, surfeit 6
External IDsOMIM: 185642; MGI: 98447; HomoloGene: 133981; GeneCards: SURF6; OMA:SURF6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278942
NM_006753

NM_009298

RefSeq (protein)

NP_001265871
NP_006744

NP_033324

Location (UCSC)Chr 9: 133.33 – 133.34 MbChr 2: 26.78 – 26.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene, being ubiquitously expressed, and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs, which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties, based on characteristics determined in mouse.[6]

References

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  1. ^ a b c ENSG00000281309 GRCh38: Ensembl release 89: ENSG00000148296, ENSG00000281309Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036160Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Duhig T, Ruhrberg C, Mor O, Fried M (May 1999). "The human Surfeit locus". Genomics. 52 (1): 72–8. doi:10.1006/geno.1998.5372. PMID 9740673.
  6. ^ a b "Entrez Gene: SURF6 surfeit 6".

Further reading

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