SLC27A3

Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene.

SLC27A3
Identifiers
Aliases	SLC27A3, ACSVL3, FATP3, VLCS-3, solute carrier family 27 member 3
External IDs	OMIM: 604193; MGI: 1347358; HomoloGene: 11529; GeneCards: SLC27A3; OMA:SLC27A3 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q21.3 Start 153,774,354 bp End 153,780,157 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 F1 Start 90,292,546 bp End 90,297,245 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte Descending thoracic aorta ascending aorta right lung gastric mucosa right coronary artery subcutaneous adipose tissue upper lobe of left lung left coronary artery monocyte Top expressed in yolk sac adrenal gland lip renal corpuscle otic vesicle embryo urethra tail of embryo embryo spermatocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function long-chain fatty acid-CoA ligase activity nucleotide binding ligase activity catalytic activity very long-chain fatty acid-CoA ligase activity long-chain fatty acid transporter activity ATP binding Cellular component integral component of membrane membrane mitochondrial membranes mitochondrion endoplasmic reticulum Biological process metabolism long-chain fatty acid metabolic process fatty acid metabolic process lipid metabolism long-chain fatty acid transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11000 26568 Ensembl ENSG00000263163 ENSG00000143554 ENSMUSG00000027932 UniProt Q5K4L6 O88561 RefSeq (mRNA) NM_024330 NM_001317929 NM_011988 NM_001316688 RefSeq (protein) NP_001304858 NP_077306 NP_001303617 NP_036118 Location (UCSC) Chr 1: 153.77 – 153.78 Mb Chr 3: 90.29 – 90.3 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

In melanocytic cells SLC27A3 gene expression may be regulated by MITF.

See also

• SLC27A3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Solute carrier family

Further reading

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Pei Z, Fraisl P, Berger J, et al. (2005). "Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells". J. Biol. Chem. 279 (52): 54454–62. doi:10.1074/jbc.M410091200. PMID 15469937.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.