SEPT14

SEPTIN14
Identifiers
Aliases	SEPTIN14, septin 14, SEPT14
External IDs	OMIM: 612140; MGI: 1921472; HomoloGene: 87501; GeneCards: SEPTIN14; OMA:SEPTIN14 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	55,862,755 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	129,785,576 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; endometrium; ; anterior pituitary; ; right lobe of liver; ; spleen; ; ganglionic eminence; ; appendix; ; body of pancreas; ; Achilles tendon;
	Top expressed in
	spermatocyte; ; secondary oocyte; ; spermatid; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; molecular adaptor activity;
Cellular component	cytoplasm; cytoskeleton; septin ring; microtubule cytoskeleton; septin complex; septin filament array;
Biological process	cell cycle; cell division; mitotic cytokinesis; septin ring assembly; cilium assembly; cytoskeleton-dependent cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
	346288
	74222
	ENSG00000154997
	ENSMUSG00000034219
	Q6ZU15
	Q9DA97
	NM_207366
	NM_028826
	NP_997249
	NP_083102
	Wikidata
View/Edit Human	View/Edit Mouse

Septin 14 is a protein that in humans is encoded by the SEPT14 gene.^[5]

Function edit

SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions.

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154997 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034219 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Septin 14".

Further reading edit

Peterson EA, Kalikin LM, Steels JD, Estey MP, Trimble WS, Petty EM (November 2007). "Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin". Mammalian Genome. 18 (11): 796–807. doi:10.1007/s00335-007-9065-x. PMID 17922164. S2CID 9906543.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000154997 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034219 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Septin 14".

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