SAMD4B

Sterile alpha motif domain containing 4B is a protein that in humans is encoded by the SAMD4B gene.

SAMD4B
Identifiers
Aliases	SAMD4B, SMGB, hSmaug2, Smaug2, sterile alpha motif domain containing 4B
External IDs	MGI: 2448542 HomoloGene: 35268 GeneCards: SAMD4B
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.2 Start 39,342,396 bp End 39,385,710 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 A3 Start 28,098,947 bp End 28,297,569 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary tibial nerve gastric mucosa canal of the cervix left lobe of thyroid gland right lobe of thyroid gland left uterine tube popliteal artery skin of abdomen right uterine tube Top expressed in lip yolk sac right ventricle superior frontal gyrus corneal stroma entorhinal cortex molar spermatid intestinal villus mucous cell of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function mRNA binding translation repressor activity RNA binding Cellular component nucleus P-body cytoplasm cytosol Biological process regulation of transcription, DNA-templated transcription, DNA-templated nuclear-transcribed mRNA poly(A) tail shortening regulation of mRNA stability negative regulation of translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55095 233033 Ensembl ENSG00000179134 ENSMUSG00000109336 UniProt Q5PRF9 Q80XS6 RefSeq (mRNA) NM_001303614 NM_018028 NM_175021 RefSeq (protein) NP_001290543 NP_060498 n/a Location (UCSC) Chr 19: 39.34 – 39.39 Mb Chr 7: 28.1 – 28.3 Mb PubMed search
Wikidata
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Further reading

• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X (May 2010). "SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity". BMB Rep. 43 (5): 355–61. doi:10.5483/bmbrep.2010.43.5.355. PMID 20510020.