RPAP2

RNA polymerase II associated protein 2, also known as RPAP2, is a human gene.

RPAP2
Identifiers
Aliases	RPAP2, C1orf82, Rtr1, RNA polymerase II associated protein 2
External IDs	OMIM: 611476 MGI: 2141142 HomoloGene: 11733 GeneCards: RPAP2
Gene location (Human) Chr. Chromosome 1 (human) Band 1p22.1 Start 92,299,059 bp End 92,402,056 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 F Start 107,745,239 bp End 107,809,704 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon cerebellar vermis corpus callosum pons thymus superior vestibular nucleus islet of Langerhans subthalamic nucleus inferior ganglion of vagus nerve gastrocnemius muscle Top expressed in secondary oocyte spermatocyte seminiferous tubule spermatid facial motor nucleus arcuate nucleus paraventricular nucleus of hypothalamus maxillary prominence proximal tubule dorsomedial hypothalamic nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function phosphoprotein phosphatase activity metal ion binding hydrolase activity RNA polymerase II CTD heptapeptide repeat phosphatase activity protein serine/threonine phosphatase activity protein binding RNA polymerase core enzyme binding Cellular component nucleolus RNA polymerase II, holoenzyme cytoplasm nucleus nucleoplasm cytosol Biological process snRNA transcription transcription, DNA-templated dephosphorylation of RNA polymerase II C-terminal domain regulation of transcription, DNA-templated snRNA transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79871 231571 Ensembl ENSG00000122484 ENSMUSG00000033773 UniProt Q8IXW5 Q8VC34 RefSeq (mRNA) NM_024813 NM_001163461 NM_001163462 NM_001289569 NM_001289570 NM_144911 NM_001359916 NM_001359917 NM_001359918 RefSeq (protein) NP_079089 NP_001156933 NP_001156934 NP_001276498 NP_001276499 NP_659160 NP_001346845 NP_001346846 NP_001346847 Location (UCSC) Chr 1: 92.3 – 92.4 Mb Chr 5: 107.75 – 107.81 Mb PubMed search
Wikidata
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Further reading

• Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Thérien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B (Jul 2007). "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme". Molecular Cell. 27 (2): 262–74. doi:10.1016/j.molcel.2007.06.027. PMC 4498903. PMID 17643375.
• Ingham RJ, Colwill K, Howard C, Dettwiler S, Lim CS, Yu J, Hersi K, Raaijmakers J, Gish G, Mbamalu G, Taylor L, Yeung B, Vassilovski G, Amin M, Chen F, Matskova L, Winberg G, Ernberg I, Linding R, O'donnell P, Starostine A, Keller W, Metalnikov P, Stark C, Pawson T (Aug 2005). "WW domains provide a platform for the assembly of multiprotein networks". Molecular and Cellular Biology. 25 (16): 7092–106. doi:10.1128/MCB.25.16.7092-7106.2005. PMC 1190255. PMID 16055720.
• Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Sowa ME, Bennett EJ, Gygi SP, Harper JW (Jul 2009). "Defining the human deubiquitinating enzyme interaction landscape". Cell. 138 (2): 389–403. doi:10.1016/j.cell.2009.04.042. PMC 2716422. PMID 19615732.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.