RDH14

Retinol dehydrogenase 14 is an enzyme that in humans is encoded by the RDH14 gene.

RDH14
Identifiers
Aliases	RDH14, PAN2, SDR7C4, retinol dehydrogenase 14 (all-trans/9-cis/11-cis), retinol dehydrogenase 14
External IDs	OMIM: 616796; MGI: 1920402; HomoloGene: 75139; GeneCards: RDH14; OMA:RDH14 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2p24.2 Start 18,554,723 bp End 18,560,679 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 A1.1 Start 10,440,772 bp End 10,445,562 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left ventricle islet of Langerhans right auricle gastrocnemius muscle skeletal muscle tissue Achilles tendon smooth muscle tissue muscle of thigh thoracic aorta ascending aorta Top expressed in interventricular septum sternocleidomastoid muscle masseter muscle digastric muscle triceps brachii muscle temporal muscle intercostal muscle epithelium of lens extraocular muscle vastus lateralis muscle More reference expression data BioGPS n/a
Gene ontology Molecular function alcohol dehydrogenase (NADP+) activity oxidoreductase activity NADP-retinol dehydrogenase activity steroid dehydrogenase activity Cellular component lysosomal membrane endoplasmic reticulum mitochondrion nucleus endoplasmic reticulum membrane membrane Biological process retinol metabolic process osteoblast differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57665 105014 Ensembl ENSG00000240857 ENSMUSG00000020621 UniProt Q9HBH5 Q9ERI6 RefSeq (mRNA) NM_020905 NM_023697 RefSeq (protein) NP_065956 NP_076186 Location (UCSC) Chr 2: 18.55 – 18.56 Mb Chr 12: 10.44 – 10.45 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Belyaeva OV, Kedishvili NY (2002). "Human pancreas protein 2 (PAN2) has a retinal reductase activity and is ubiquitously expressed in human tissues". FEBS Lett. 531 (3): 489–93. Bibcode:2002FEBSL.531..489B. doi:10.1016/S0014-5793(02)03588-3. PMID 12435598. S2CID 22343979.
• Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, Del Val C, Arlt D, Hahne F, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.