DNA-directed RNA polymerase III subunit RPC9 is an enzyme that in humans is encoded by the CRCP gene.[5][6][7][8]

CRCP
Identifiers
AliasesCRCP, CGRP-RCP, CGRPRCP, RCP, RCP9, CGRP receptor component, RPC9, POLR3I, POLR3J, C17
External IDsOMIM: 606121; MGI: 1100818; HomoloGene: 40587; GeneCards: CRCP; OMA:CRCP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001040647
NM_001040648
NM_001142414
NM_014478

NM_007761

RefSeq (protein)

NP_001035737
NP_001035738
NP_001135886
NP_055293

NP_031787

Location (UCSC)Chr 7: 66.11 – 66.15 MbChr 5: 130.06 – 130.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[8]


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000241258Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025532Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Luebke AE, Dahl GP, Roos BA, Dickerson IM (Jun 1996). "Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay". Proc Natl Acad Sci U S A. 93 (8): 3455–60. Bibcode:1996PNAS...93.3455L. doi:10.1073/pnas.93.8.3455. PMC 39630. PMID 8622957.
  6. ^ Balkan W, Oates EL, Howard GA, Roos BA (Mar 1999). "Testes exhibit elevated expression of calcitonin gene-related peptide receptor component protein". Endocrinology. 140 (3): 1459–69. doi:10.1210/endo.140.3.6541. PMID 10067875.
  7. ^ Siaut M, Zaros C, Levivier E, Ferri ML, Court M, Werner M, Callebaut I, Thuriaux P, Sentenac A, Conesa C (Dec 2002). "An Rpb4/Rpb7-Like Complex in Yeast RNA Polymerase III Contains the Orthologue of Mammalian CGRP-RCP". Mol Cell Biol. 23 (1): 195–205. doi:10.1128/MCB.23.1.195-205.2003. PMC 140662. PMID 12482973.
  8. ^ a b "Entrez Gene: RCP9 calcitonin gene-related peptide-receptor component protein".

Further reading

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