Protoporphyrinogen IX dehydrogenase (menaquinone)

Protoporphyrinogen IX dehydrogenase (menaquinone) (EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase.[1] This enzyme catalyses the following chemical reaction

Protoporphyrinogen IX dehydrogenase (menaquinone)
Identifiers
EC no.1.3.5.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
protoporphyrinogen IX + 3 menaquinone protoporphyrin IX + 3 menaquinol

This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.

References

edit
  1. ^ Boynton TO, Daugherty LE, Dailey TA, Dailey HA (July 2009). "Identification of Escherichia coli HemG as a novel, menadione-dependent flavodoxin with protoporphyrinogen oxidase activity". Biochemistry. 48 (29): 6705–11. doi:10.1021/bi900850y. PMC 2749469. PMID 19583219.
edit