Primary olfactory cortex

The primary olfactory cortex (POC) is a portion of the cerebral cortex. It is found in the inferior part of the temporal lobe of the brain. It receives input from the olfactory tract. It is involved in the sense of smell (olfaction).

Primary olfactory cortex
SystemOlfactory system
LocationInferior temporal lobe
PartsAnterior olfactory nucleus, piriform cortex, olfactory tubercle, amygdala, entorhinal cortex, periamygdaloid cortex
FunctionSense of smell
NeuroLex IDbirnlex_2706
Anatomical terms of neuroanatomy


The primary olfactory cortex is in the inferior part of the temporal lobe of the brain.[1] It involves the anterior olfactory nucleus,[2] the piriform cortex,[2] the olfactory tubercle,[2] part of the amygdala,[2] part of the entorhinal cortex,[2][3] and the periamygdaloid cortex.[2][4] Some sources state that it also includes the prepyriform area.[3][4]

The primary olfactory cortex receives fibres from the olfactory tract.[5] It receives input from mitral cells and tufted cells.[5][6] These cells do not pass through the thalamus.[1] The primary olfactory cortex then sends fibres to the hippocampus, thalamus, and the hypothalamus.[2]


The primary olfactory cortex is involved in the sense of smell (olfaction).[7][8]


  1. ^ a b Feher, Joseph (2012). "4.6 - The Chemical Senses". Quantitative Human Physiology. Academic Press. pp. 359–369. doi:10.1016/B978-0-12-382163-8.00039-6. ISBN 978-0-12-382163-8.
  2. ^ a b c d e f g Cersosimo, Maria Graciela; Benarroch, Eduardo E.; Raina, Gabriela B. (2021). "16 - Lewy bodies in the olfactory system and the hypothalamus". Handbook of Clinical Neurology. Vol. 182. Elsevier. pp. 235–244. doi:10.1016/B978-0-12-819973-2.00016-2. ISBN 978-0-12-819973-2. ISSN 0072-9752.
  3. ^ a b "Anatomy of Olfactory System: eMedicine Clinical Procedures". Retrieved 2009-11-20.
  4. ^ a b Fix, James D. (2002). Neuroanatomy. Hagerstwon, MD: Lippincott Williams & Wilkins. pp. 326. ISBN 0-7817-2829-0.
  5. ^ a b Ennis, Matthew; Puche, Adam C.; Holy, Tim; Shipley, Michael T. (2015). "27 - The Olfactory System". The Rat Nervous System (4th ed.). Academic Press. pp. 761–803. doi:10.1016/B978-0-12-374245-2.00027-9. ISBN 978-0-12-374245-2.
  6. ^ Doty, R. L. (2017). "Sense of Smell". Reference Module in Neuroscience and Biobehavioral Psychology. Elsevier. doi:10.1016/B978-0-12-809324-5.06559-7. ISBN 978-0-12-809324-5.
  7. ^ Zelano C, Montag J, Khan R, Sobel N (2009). "A specialized odor memory buffer in primary olfactory cortex". PLOS ONE. 4 (3): e4965. Bibcode:2009PLoSO...4.4965Z. doi:10.1371/journal.pone.0004965. PMC 2654926. PMID 19305509.
  8. ^ Johnson DM, Illig KR, Behan M, Haberly LB (September 2000). "New features of connectivity in piriform cortex visualized by intracellular injection of pyramidal cells suggest that "primary" olfactory cortex functions like "association" cortex in other sensory systems". J. Neurosci. 20 (18): 6974–82. doi:10.1523/JNEUROSCI.20-18-06974.2000. PMC 6772836. PMID 10995842.

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