San Angelo is a city in and the county seat of Tom Green County, Texas. It is also the principal city of the 'San Angelo, Texas Metropolitan Statistical Area' which encompasses all of both Irion and Tom Green counties. As of the 2000 census, San Angelo had a total population of 88,439. The city is located at the confluence of the North - South Concho River, a tributary of the Colorado River.

It is home to the Fort Concho National Historic Landmark. Goodfellow Air Force Base is also located at the city's outskirts. Mathis Field (also known as San Angelo Regional Airport) is the commercial airport serving the city. San Angelo's main newspaper is the San Angelo Standard-Times.