April 4, 2006 (Tuesday)
- 2006 labor protests in France: Three million people march against the First Employment Contract (CPE) law, 700 000 in Paris. Student organizations call for a general strike. (Washington Post) Archived 2012-11-02 at the Wayback Machine
- In the Republic of Ireland, Denis Donaldson a former senior Sinn Féin member, is found shot dead near the village of Glenties, County Donegal, close to where it is believed he had been living since he admitted, in December 2005, to being a paid British agent for over twenty years. (BBC)
- Thailand legislative election, April 2006: Thaksin Shinawatra resigns as Prime Minister of Thailand despite his ruling Thai Rak Thai party winning an overwhelming majority in the House of Representatives. (BBC)
- A security expert testifies to an inquest that film director James Miller was shot intentionally by an Israeli soldier while making a film in a Palestinian refugee camp in the Gaza Strip. (The Independent) (BBC)
- Former Majority Leader Tom DeLay announces his resignation from the United States House of Representatives. (TIME) Archived 2013-08-23 at the Wayback Machine
- The 39th Canadian Parliament opens in Ottawa, with the Speech from the Throne delivered by the Governor General on behalf of the newly elected government of Stephen Harper. (Toronto Star)