Poly drug use
Poly drug use (or polysubstance use) refers to the use of combined psychoactive substances to achieve a particular effect. In many cases one drug is used as a base or primary drug, with additional drugs to leaven or compensate for the side effects of the primary drug and make the experience more enjoyable with drug synergy effects, or to supplement for primary drug when supply is low.
|Poly drug use|
|Caffeinated alcoholic beverages, such as this Vodka Red Bull are widespread and legal.|
|Complications||Combined drug intoxication, drug overdose|
This section needs additional citations for verification. (August 2018)
|Drug 2||Drug 3||Poly drug name||Intoxication name||Comment|
|Any drug||Black tar heroin||Whoonga||Widespread use in South Africa|
|Any drug||Cannabis||Amp joint||Marijuana cigarette laced with some form of narcotic|
|Any drug||Nicotine||Cooler||A cigarette laced with a drug|
|Any depressant||Any stimulant||Over and under|
|Any pharmaceutical||Any pharmaceutical||Polypharmacy. Pharming|
|2C-B||MDMA||Nexus Flip||Nexus Flipping|
|Alcohol||Caffeine||Caffeinated alcoholic drink|
|Alcohol||Cannabis||Herb and Al. Judgement Day||Cross fading||Called Judgement Day in Ghana when cannabis is added to the drink|
|Alcohol||Cocaine||Snow-coning||Metabolized into cocaethylene|
|Amphetamine||Xanax||Orange Dream Blossom||Cloud Rush||The combination is crushed together and insufflated|
|Banisteriopsis caapi||β-Carbolines containing plants (e.g. Peganum harmala)||Ayahuasca, changa||Ayahuasca is drunk. Changa is smoked or vaped.|
|Barbiturates||Alcohol||Used to be common, when Barbiturates were more readily available|
|Caffeine||Methamphetamine||Biker's coffee. Kamikaze, ya ba|
|Cannabis||Crack-cocaine||Crack weed (less known: champagne, chronic, cocktail, dirty joint, fry daddy, gimmie, gremmies, juice joint, lace, oolies, p dog, primo, splitting, thirty eight, turbo, wollie, yeola)||Cocoa puffs|
|Cannabis||Heroin||Atom bomb, stuff|
|Cannabis||Heroin or opium||A-bomb|
|Cannabis||PCP||Killer weed (less known: Bionic, clickums, donk, dust blunt, illies, illing, leak, love leaf, lovelies, parsley, wet, zoom)||Wet is cannabis dipped in PCP|
|Cannabis||Nicotine||Blunt, joint, spliff||A rolled marijuana cigarette usually made with rolling paper. A blunt is a cigar hollowed out and filled with marijuana. It is rolled with the tobacco-leaf "wrapper" from an inexpensive cigar. Blunts take their name from Phillies Blunt brand cigars.|
|Cocaine||Heroin||Snowball. Other names: Belushi, bombita, murder one, whiz bang||Snowballing|
|Cocaine||Heroin||Nicotine||flamethrower, primos||Cigarette laced with cocaine and heroin|
|Cocaine||Heroin or morphine||Powerball, speedball||Powerballing, speedballing||Speedballing, powerballing is often used to describe intravenous use. The term can also be applied to use of pharmaceutical opioids, benzodiazepines or barbiturates along with stimulants.|
|Cocaine||Ketamine||CK1, Calvin Klein, cable|
|Cocaine||LSD||Cracid (or outer limits)||Cracid is a portmanteau of cocaine and acid|
|Cocaine||Morphine||C & M|
|Codeine||Glutethimide||Pancakes and syrups||Combination of glutethimide and codeine cough syrup|
|Crack-cocaine||Fentanyl||Dirty fentanyl, takeover|
|Crack-cocaine||Heroin||Chocolate rock, dragon rock, eightball, moonrock, smoking gun, tar|
|Crack-cocaine||PCP||Nicotine||Ozone||PCP and crack cigarette|
|Crack-cocaine||PCP||Missile basing, P-funk, space basing, spaceball, space cadet, space dust, tragic magic|
|Crack-cocaine||Nicotine||Coolie, crimmie, woolas||A cigarette laced with crack|
|DXM||Psilocybin or psilocybin mushroom||Cherry-bombing|
|Any Dissociative||Any Dissociative||Void flip|
|Fentanyl||Heroin||Birria, chiva loca, Facebook||Facebook is mixed in a pill form|
|Hashish||Belladonna||Alamout black hash||Mixed|
|Hashish||LSD||Royal temple ball||The hashish is mixed with LSD and rolled into a ball intended for oral use, because LSD cannot be smoked.|
|Hashish||Opium||Black hash, black Russian|
|Heroin||Morphine||New Jack swing|
|Heroin||PCP||Alien sex fiend|
|Heroin||Xylazine||Anestesiade caballo||Xylazine is a horse anesthetic|
|LSD||Marijuana||Amphetamine||Hippie heart attack|
|LSD||MDMA||2C-B||Granny Flip, Coiled Flip|
|LSD||Psilocybin or psilocybin mushroom||God's flesh, Soul Bomb|
|Psilocybin or psilocybin mushroom||DMT||Terence flip|
|LSD||DMT||Cosmo flip||Cosmo flipping|
|MDMA||Alcohol||Tipsy flip||Tipsy flipping|
|MDMA||Cannabis||Stoner flip||Stoner flipping|
|MDMA||Cocaine||Sugar flip||Sugar flipping|
|MDMA||Cocaine||LSD||Candy-flip on a string||Candy-flipping on a string|
|MDMA||DMT||Shaman flip, time flip||Shaman flipping, time flipping|
|MDMA||DXM||Robo flip||Robo flipping|
|MDMA||GHB||Gamma flip||Gamma flipping|
|MDMA||Ketamine||Kitty flip||Kitty flipping|
|MDMA||LSD||Candy flip||Candy flipping|
|MDMA||LSD||Ketamine||Holy Trident||Holy Tridenting|
|MDMA||LSD||Psilocybin or psilocybin mushroom||Jedi flip, twilight flip||Jedi flipping, twilight flipping|
|MDMA||Mescaline or psychoactive cactus||Love flip, love trip||Love flipping|
|MDMA||Methadone||Chocolate flip||Chocolate flipping|
|MDMA||Methamphetamine||Trailer flip||Trailer flipping|
|MDMA||Opiates||Poppy flip||Poppy flipping|
|MDMA||PCP||Domex, elephant flip||Elephant flipping|
|MDMA||Psilocybin or psilocybin mushroom||Hippy flip, flower flip, ethno flip||Hippy flipping, flower flipping, ethno flipping|
|MDMA||Diphenhydramine or Any deliriant||Nightmare flip||Nightmare flipping|
|MDMA||Sildenafil||Sextasy (or hammerheading)|
|DXM||Diphenhydramine||Otc flip||Robowalking on a string|
|Diphenhydramine||Caffeine||Sleep walking||Sleep walking|
|LSD||Psilocybin or psilocybin mushroom||DMT||Super flip||Super flipping||Take LSD and shrooms then at the come up smoke DMT|
|MDMA||Xanax||Zen flip||Zen flipping|
Poly drug use often carries with it more risk than use of a single drug, due to an increase in side effects, and drug synergy. The potentiating effect of one drug on another is sometimes considerable and here the licit drugs and medicines – such as alcohol, nicotine and antidepressants – have to be considered in conjunction with the controlled psychoactive substances. The risk level will depend on the dosage level of both substances. If the drugs taken are illegal, they have a chance of being mixed (also known as "cutting") with other substances which dealers are reported to do to increase the perceived quantity when selling to others to increase their returns. This is particularly common with powdered drugs such as cocaine or MDMA which can be mixed with relative ease by adding another white powdery substance to the drug. This cumulative effect can lead to further unintended harm to health dependent on what is being covertly added. Concerns also exist about a number of pharmacological pairings: alcohol and cocaine increase cardiovascular toxicity; alcohol or depressant drugs, when taken with opioids, lead to an increased risk of overdose; and opioids or cocaine taken with ecstasy or amphetamines also result in additional acute toxicity. Benzodiazepines can cause death when mixed with other CNS depressants such as opioids, alcohol, or barbiturates.
Within the general concept of multiple drug use, several specific meanings of the term must be considered. At one extreme is planned use, where the effects of more than one drug are taken for a desired effect. Another type is when other drugs are used to counteract the negative side effects of a different drug (e.g. depressants are used to counteract anxiety and restlessness from taking stimulants). On the other hand, the use of several substances in an intensive and chaotic way, simultaneously or consecutively, in many cases each drug substituting for another according to availability.
The phenomenon is the subject of established academic literature.
A study among treatment admissions found that it is more common for younger people to report poly drug use.
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- "Polydrug Use Among Treatment Admissions: 1998." OAS Home: Alcohol, Tobacco & Drug Abuse and Mental Health Data from SAMHSA, Office of Applied Studies. Web. 29 Sept. 2011.