The enzyme pentalenene synthase (EC 4.2.3.7) catalyzes the chemical reaction

pentalenene synthase
Identifiers
EC no.4.2.3.7
CAS no.90597-46-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
(2E,6E)-farnesyl diphosphate pentalenene + diphosphate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming). This enzyme is also called pentalenene synthetase.

References

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  • Cane DE (1983). "Cell-free studies of monoterpene and sesquiterpene biosynthesis". Biochem. Soc. Trans. 11 (5): 510–5. PMID 6642060.
  • Cane DE, Tillman AM (1983). "Pentalenene biosynthesis and the enzymic cyclization of farnesyl pyrophosphate". J. Am. Chem. Soc. 105: 122–124. doi:10.1021/ja00339a026.
  • Cane, DE, Hubbard BR; Sohng, JK; Lamberson, CR; Rudnicki, SM; Wu, Z; Lloyd, MD; Oliver, JS; Hubbard, BR (1994). "Pentalenene synthase. Purification, molecular cloning, sequencing, and high-level expression in Escherichia coli of a terpenoid cyclase from Streptomyces UC5319". Biochemistry. 33 (19): 5846–57. doi:10.1021/bi00185a024. PMID 8180213.{{cite journal}}: CS1 maint: multiple names: authors list (link)