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Paula Cannon is a British geneticist and virologist, Distinguished Professor of Molecular Microbiology & Immunology at the University of Southern California.[1] She is a specialist in gene therapy, hematopoietic stem cells, and human immunodeficiency virus (HIV) with particular interest in gene editing and humanized mice.
Paula Cannon | |
|---|---|
| Nationality | British |
| Alma mater | University of Liverpool, UK |
| Scientific career | |
| Fields | Genetics |
| Institutions | University of Southern California (USC) |
Personal life and education
editShe received her PhD from the University of Liverpool, and postdoctoral training at both Oxford and Harvard[1]
Academic career
editCannon's recent work is aimed at disrupting the CCR viral co-receptor, CCR5, using zinc finger nucleases(ZFNs). She also studies SARS-CoV-2 and highly pathogenic hemorrhagic fever viruses, including Ebola and Lassa fever viruses.[1]
Selected publications
editHer most cited peer-reviewed publications are:
- Soneoka Y, Cannon PM, Ramsdale EE, Griffiths JC, Romano G, Kingsman SM, Kingsman AJ. A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids research. 1995 Feb 25;23(4):628-33. [2] open access Cited 932 times, according to Google Scholar,[2]
- Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, Cannon PM. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nature Biotechnology. 2010 Aug;28(8):839-47. Cited 762 times, according to Google Scholar [2]
- Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature Medicine. 2016 Aug;22(8):839-50. [3] Cited 375 times, according to Google Scholar [2]
- Gardner MR, Kattenhorn LM, Kondur HR, Von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015 Mar;519(7541):87-91. [4] Cited 275 times, according to Google Scholar [2]
- Wang J, Exline CM, DeClercq JJ, Llewellyn GN, Hayward SB, Li PW, Shivak DA, Surosky RT, Gregory PD, Holmes MC, Cannon PM. Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors. Nature biotechnology. 2015 Dec;33(12):1256-63. Cited 242 times, according to Google Scholar [2]
References
editExternal links
edit- Paula Cannon publications indexed by Google Scholar