Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1, also known as PTENP1, is a human pseudogene.[3] which has a partial reactivated function as a competing endogenous RNA regulating the tumor suppressor gene PTEN.[4]

PTENP1
Identifiers
AliasesPTENP1, PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN, phosphatase and tensin homolog pseudogene 1
External IDsOMIM: 613531; GeneCards: PTENP1; OMA:PTENP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

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RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 9: 33.67 – 33.68 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000237984Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: PTENP1 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1".
  4. ^ Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP (June 2010). "A coding-independent function of gene and pseudogene mRNAs regulates tumour biology". Nature. 465 (7301): 1033–8. Bibcode:2010Natur.465.1033P. doi:10.1038/nature09144. PMC 3206313. PMID 20577206.*Lay summary in: Buehler J (September 1, 2021). "The Complex Truth About 'Junk DNA'". Quanta Magazine.

Further reading

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