OR10G3

Olfactory receptor 10G3 is a protein that in humans is encoded by the OR10G3 gene.

OR10G3
Identifiers
Aliases	OR10G3, olfactory receptor, family 10, subfamily G, member 3, OR14-40, olfactory receptor family 10 subfamily G member 3
External IDs	MGI: 3031346; HomoloGene: 27165; GeneCards: OR10G3; OMA:OR10G3 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q11.2 Start 21,568,520 bp End 21,580,076 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 C2 Start 52,608,789 bp End 52,616,625 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle right lung pituitary gland anterior pituitary blood right lobe of liver granulocyte stromal cell of endometrium subcutaneous adipose tissue Achilles tendon Top expressed in blastocyst embryo hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26533 258424 Ensembl ENSG00000169208 ENSMUSG00000094140 UniProt Q8NGC4 Q8VF72 RefSeq (mRNA) NM_001005465 NM_146432 RefSeq (protein) NP_001005465 NP_666643 Location (UCSC) Chr 14: 21.57 – 21.58 Mb Chr 14: 52.61 – 52.62 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Boysen C, Simon MI, Hood L (1997). "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4): 330–8. doi:10.1101/gr.7.4.330. PMID 9110172.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR10G3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.