Naringenin 7-O-methyltransferase

Naringenin 7-O-methyltransferase (EC 2.1.1.232, NOMT) (full systematic name S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase) is a methyltransferase isolated from rice, which catalyzes the biosynthesis of sakuranetin.[1]

Naringenin 7-O-methyltransferase
Identifiers
EC no.2.1.1.232
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

This enzyme catalyses the following chemical reaction:

S-adenosyl-L-methionine + (2S)-naringenin S-adenosyl-L-homocysteine + (2S)-sakuranetin

While the enzyme is not present in healthy rice leaves, it can be induced by treatment with ultraviolet radiation, jasmonic acid and copper chloride.[1]

References

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  1. ^ a b Rakwal R, Agrawal GK, Yonekura M, Kodama O (June 2000). "Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.)". Plant Science. 155 (2): 213–221. doi:10.1016/s0168-9452(00)00223-5. PMID 10814825.
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