NOB1

RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene.

NOB1
Identifiers
Aliases	NOB1, ART-4, MST158, NOB1P, PSMD8BP1, MSTP158, NIN1/PSMD8 binding protein 1 homolog, NIN1 (RPN12) binding protein 1 homolog
External IDs	OMIM: 613586; MGI: 1914869; HomoloGene: 31924; GeneCards: NOB1; OMA:NOB1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16q22.1 Start 69,741,871 bp End 69,754,926 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8|8 D3 Start 108,139,118 bp End 108,151,683 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas right adrenal gland right adrenal cortex left adrenal gland left adrenal cortex left ovary stromal cell of endometrium uterine tube right ovary mucosa of esophagus Top expressed in hand epiblast morula embryo embryo primitive streak otolith organ utricle ventricular zone foot More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding endoribonuclease activity Cellular component preribosome, small subunit precursor nucleus cytosol nucleoplasm Biological process maturation of SSU-rRNA visual perception RNA phosphodiester bond hydrolysis, endonucleolytic rRNA processing cleavage involved in rRNA processing ribosomal small subunit biogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 28987 67619 Ensembl ENSG00000141101 ENSMUSG00000003848 UniProt Q9ULX3 Q8BW10 RefSeq (mRNA) NM_014062 NM_026277 RefSeq (protein) NP_054781 NP_080553 Location (UCSC) Chr 16: 69.74 – 69.75 Mb Chr 8: 108.14 – 108.15 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Fatica A, Oeffinger M, Dlakić M, Tollervey D (2003). "Nob1p is required for cleavage of the 3' end of 18S rRNA". Mol. Cell. Biol. 23 (5): 1798–807. doi:10.1128/MCB.23.5.1798-1807.2003. PMC 151717. PMID 12588997.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Daniele A, Altruda F, Ferrone M, et al. (1992). "Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli". Mol. Cell. Biochem. 107 (2): 87–94. doi:10.1007/bf00225511. PMID 1791827. S2CID 25617287.