Monocyte distribution width (MDW) is a cytometry-based parameter that measures the range of variation of monocytes. If the parameter is available, it is reported as part of the standard complete blood count (CBC) with differential.[1]
| Monocyte distribution width | |
|---|---|
| Synonyms | MDW |
| Purpose | measure of the range of variation of monocyte volume |
The parameter was FDA cleared as an early sepsis indicator for ER patients in 2019 for Beckman Coulter.[2][3]
MDW serves as an indicator for early screening of sepsis in conjunction with CRP and PCT and for differentiating false positive blood cultures.[4][5]
References edit
- ^ Bentahar, Ahmed (Sep 1, 2022). "What is Monocyte Distribution Width". Beckman Coulter.
- ^ "Beckman Coulter's Early Sepsis Indicator Receives 510(k) Clearance from the U.S. Food and Drug Administration". www.beckmancoulter.com. April 18, 2019.
- ^ "FDA Product Classification". FDA.
- ^ Jo, Sung Jin; Kim, Sei Won; Choi, Jung-Hyun; Choi, Seoung Pill; Lee, Jehoon; Lim, Jihyang (20 December 2022). "Monocyte distribution width (MDW) as a useful indicator for early screening of sepsis and discriminating false positive blood cultures". PLOS ONE. 17 (12): e0279374. Bibcode:2022PLoSO..1779374J. doi:10.1371/journal.pone.0279374. PMC 9767324. PMID 36538555.
- ^ Paxton, Anne (18 July 2023). "For sepsis Dx, MDW biomarker brought into the mix - CAP TODAY". CAP Today. Retrieved 16 April 2024.
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