Momilactone-A synthase

Momilactone-A synthase (EC 1.1.1.295, momilactone A synthase, OsMAS) is an enzyme with systematic name 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide:NAD(P)+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

Momilactone-A synthase
Identifiers
EC no.1.1.1.295
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P)+ momilactone A + NAD(P)H + H+

The rice phytoalexin momilactone A is a diterpenoid secondary metabolite that is involved in the defense mechanism of the plant. Momilactone A is produced in response to attack by a pathogen through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation.

References

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  1. ^ Atawong A, Hasegawa M, Kodama O (March 2002). "Biosynthesis of rice phytoalexin: enzymatic conversion of 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide to momilactone A". Bioscience, Biotechnology, and Biochemistry. 66 (3): 566–70. doi:10.1271/bbb.66.566. PMID 12005050. S2CID 83339044.
  2. ^ Shimura K, Okada A, Okada K, Jikumaru Y, Ko KW, Toyomasu T, Sassa T, Hasegawa M, Kodama O, Shibuya N, Koga J, Nojiri H, Yamane H (November 2007). "Identification of a biosynthetic gene cluster in rice for momilactones". The Journal of Biological Chemistry. 282 (47): 34013–8. doi:10.1074/jbc.M703344200. PMID 17872948.
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