Molybdenum cofactor cytidylyltransferase (EC 2.7.7.76, MocA, CTP:molybdopterin cytidylyltransferase, MoCo cytidylyltransferase, Mo-MPT cytidyltransferase) is an enzyme with systematic name CTP:molybdenum cofactor cytidylyltransferase.[1][2] This enzyme catalyses the following chemical reaction:
| Molybdenum cofactor cytidylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.76 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- CTP + molybdenum cofactor diphosphate + cytidylyl molybdenum cofactor
Catalyses the cytidylation of the molybdenum cofactor.
References
edit- ^ Neumann M, Mittelstädt G, Seduk F, Iobbi-Nivol C, Leimkühler S (August 2009). "MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli". The Journal of Biological Chemistry. 284 (33): 21891–8. doi:10.1074/jbc.M109.008565. PMC 2755913. PMID 19542235.
- ^ Neumann M, Seduk F, Iobbi-Nivol C, Leimkühler S (January 2011). "Molybdopterin dinucleotide biosynthesis in Escherichia coli: identification of amino acid residues of molybdopterin dinucleotide transferases that determine specificity for binding of guanine or cytosine nucleotides". The Journal of Biological Chemistry. 286 (2): 1400–8. doi:10.1074/jbc.M110.155671. PMC 3020748. PMID 21081498.
External links
edit- Molybdenum+cofactor+cytidylyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
