Maria Josepha of Saxony may refer to:
- Princess Maria Josepha of Saxony (1731–1767), daughter of Augustus III of Poland
- Maria Josepha Amalia of Saxony (1803–1829), daughter of Maximilian, Hereditary Prince of Saxony
- Princess Maria Josepha of Saxony (1867–1944), daughter of George, King of Saxony
- Princess Maria Josepha of Saxony (1928–2018), daughter of Friedrich Christian, Margrave of Meissen
- Maria Josepha of Austria (1699–1757), wife of Augustus III of Poland