Mammaglobin-B also known as secretoglobin family 2A member 1 is a protein that in humans is encoded by the SCGB2A1 gene.[5][6]

SCGB2A1
Identifiers
AliasesSCGB2A1, LPHC, LPNC, MGB2, UGB3, secretoglobin family 2A member 1
External IDsOMIM: 604398; HomoloGene: 88664; GeneCards: SCGB2A1; OMA:SCGB2A1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002407

XM_006527538

RefSeq (protein)

NP_002398

NP_001365339

Location (UCSC)Chr 11: 62.21 – 62.21 MbChr 19: 9.85 – 9.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SCGB2A1 and breast cancer

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SCGB2A1 expression is highly specific of mammary tissue, and has been used for identification and detection of disseminated breast cancer cells.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124939Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000096872Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Becker RM, Darrow C, Zimonjic DB, Popescu NC, Watson MA, Fleming TP (Jan 1999). "Identification of mammaglobin B, a novel member of the uteroglobin gene family". Genomics. 54 (1): 70–8. doi:10.1006/geno.1998.5539. PMID 9806831.
  6. ^ "Entrez Gene: SCGB2A1 secretoglobin, family 2A, member 1".
  7. ^ Lacroix, M (2006). "Significance, detection and markers of disseminated breast cancer cells". Endocrine-Related Cancer. 13 (4). Bioscientifica: 1033–1067. doi:10.1677/ERC-06-0001. PMID 17158753.

Further reading

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