Mps one binder kinase activator-like 1A, also known as Mob1 homolog 1A, is a protein that in humans is encoded by the MOBKL1A gene.[5][6]

MOB1B
Identifiers
AliasesMOB1B, MATS2, MOB4A, MOBKL1A, MOB kinase activator 1B
External IDsOMIM: 609282; MGI: 1915723; HomoloGene: 61676; GeneCards: MOB1B; OMA:MOB1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001244766
NM_001244767
NM_173468

NM_026735

RefSeq (protein)

NP_001231695
NP_001231696
NP_775739

NP_081011

Location (UCSC)Chr 4: 70.9 – 71.02 MbChr 5: 88.87 – 88.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173542Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000006262Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: MOB1".
  6. ^ Devroe E, Erdjument-Bromage H, Tempst P, Silver PA (June 2004). "Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases". J. Biol. Chem. 279 (23): 24444–51. doi:10.1074/jbc.M401999200. PMID 15067004.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.