Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.[5][6]

MLLT10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMLLT10, AF10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, histone lysine methyltransferase DOT1L cofactor, MLLT10 histone lysine methyltransferase DOT1L cofactor
External IDsOMIM: 602409; MGI: 1329038; HomoloGene: 20973; GeneCards: MLLT10; OMA:MLLT10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001252560
NM_001252561
NM_010804

RefSeq (protein)

NP_001239489
NP_001239490
NP_034934

Location (UCSC)Chr 10: 21.52 – 21.74 MbChr 2: 18.06 – 18.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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MLLT10 has been shown to interact with SS18.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000078403Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026743Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R, Young BD (Apr 1995). "A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia". Blood. 85 (6): 1435–41. doi:10.1182/blood.V85.6.1435.bloodjournal8561435. PMID 7888665.
  6. ^ "Entrez Gene: MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10".
  7. ^ de Bruijn DR, dos Santos NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A (May 2001). "The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10". Oncogene. 20 (25): 3281–9. doi:10.1038/sj.onc.1204419. PMID 11423977. S2CID 2364045.

Further reading

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